The Miami and Erie Canal operated in the 1840 and 1860 era.  This byway follows SR 66 and the canal corridor from Johnson Farm at Piqua, in Miami County, northward through Minster, New Bremen, St. Mary's and Spencerville, ending in Delphos in Allen County, a distance of 50 miles. 

• Maumee. Side Cut Metropark, W of Maumee off US 24. Three of the original six locks of the Maumee Side Cut, which lowered canal boats into the Maumee River. Picnicking and hiking.
• Waterville. Farnsworth, Bend View and Providence Metroparks are interconnected by an 8-mile hiking trail along the towpath leading to Providence Dam. Ludwig Mill, a working, water-powered facility near the dam is open on Sunday, May-October. Lock 9 lies adjacent to mill.
• Grand Rapids. Mary Jane Thurston State Park on SR 65 provides access to Grand Rapids Dam and the adjacent guard lock for the Gilead Side Cut to Grand Rapids. The dam created a slack-water pool in the river for canal boats. Towpath hiking along the side cut. Canal boat ride through a working lock.
• Delphos. The Miami and Erie Trail, a 40-mile long section of the old towpath, extends southward from Delphos to Lake Loramie State Park. Many lock sites, Deep Cut, Forty Acre Pond and several canal towns lie along this attractive hiking trail.
• Spencerville. Deep Cut, 2 miles S of SR 66 is a 6,600-foot long excavation to carry the canal through a glacial moraine. A National Historic Landmark. Picnicking and hiking.

Additional Points of Interest